About the Company
GlaxoSmithKline (GSK) is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people over the next 10 years. Our pipeline is focused on the science of the immune system, human genetics and advanced technologies to deliver transformative medicines and vaccines.
Job Description
We are seeking a highly motivated and skilled Biochemist to join our dynamic R&D team in Southampton. The successful candidate will be instrumental in designing and executing complex biochemical assays, contributing to the discovery and development of novel therapeutic compounds across various disease areas.
Key Responsibilities
- Design, develop, and optimize a variety of biochemical and cell-based assays for target validation and lead compound screening.
- Conduct experiments to investigate enzyme kinetics, protein-ligand interactions, and cellular mechanisms of action.
- Analyze and interpret complex experimental data, preparing detailed reports and presentations for internal and external stakeholders.
- Operate and maintain specialized laboratory equipment, including but not limited to HPLC, mass spectrometers, liquid handling systems, and plate readers.
- Collaborate cross-functionally with medicinal chemists, biologists, pharmacologists, and computational scientists.
- Maintain accurate and detailed laboratory records in compliance with GLP standards and company policies.
- Contribute to scientific publications, patent applications, and intellectual property development.
- Stay abreast of new scientific literature and technologies in biochemistry and drug discovery.
Required Skills
- Extensive hands-on experience with biochemical assay development, optimization, and validation.
- Proficiency in protein purification, characterization, and handling techniques.
- Strong analytical and problem-solving skills with meticulous attention to detail.
- Excellent written and verbal communication abilities for presenting complex scientific data.
- Ability to work both independently and effectively within a collaborative, multidisciplinary team environment.
- Thorough understanding of laboratory safety protocols and regulatory guidelines (e.g., GLP).
- Familiarity with data analysis software (e.g., GraphPad Prism, Excel).
Preferred Qualifications
- PhD in Biochemistry, Molecular Biology, Biophysics, or a closely related scientific field.
- Prior industry experience (2+ years) in pharmaceutical or biotechnology R&D.
- Experience with high-throughput screening (HTS) and automation.
- Knowledge of bioinformatics tools for large-scale data analysis.
- Familiarity with drug discovery processes and preclinical development stages.
- Experience with structural biology techniques (e.g., X-ray crystallography, NMR) or cryo-EM.
Perks & Benefits
- Competitive annual salary and performance-based bonuses.
- Comprehensive health, dental, and vision insurance coverage.
- Generous pension scheme with company contributions.
- Paid time off, including annual leave and public holidays.
- Opportunities for continuous professional development, training, and career advancement.
- On-site fitness center and comprehensive wellness programs.
- Employee assistance program and mental health support.
- Subsidized on-site cafeteria and employee discounts.
- Flexible working options where applicable.
How to Apply
If you are interested in this position, please click the "Apply Now" button below. To ensure your application is properly considered, please prepare the following:
- An up-to-date Resume or CV
- A brief cover letter summarizing your experience and motivation
Applications are reviewed on a rolling basis. Only shortlisted candidates will be contacted for an interview.
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